A number of clinical trials have established a clear link between magnesium and the development of migraine. Magnesium is involved in the release of nitric acid, a chemical that dilates blood vessels, as well as a number of migraine related receptors and neurotransmitters. Studies show that up to 50% of migraine sufferers are deficient in magnesium during an acute attack and that the infusion with magnesium gives rapid relief.

In a placebo controlled, double blind randomized study, attack frequency was reduced by 41.6% in the group taking 600 mg magnesium daily over 12 weeks and by only 15% in the placebo group. Drug consumption for symptomatic relief and the number of days with migraine were also significantly reduced by the supplementation of this mineral.

 All magnesiums are not created equal.

 Note: The best forms of supplemental magnesium to ensure effective absorption is magnesium aspartate, orotate, diglycinate, or citrate. Beware of magnesium carbonate, oxide (very dependent on hydrochloric acid) or sulfate (laxative effect).